The dosage of ivermectin (12 mg) for scabies is determined by the patient’s body weight. The standard recommended dosage is an oral dose of 200 micrograms (mcg) per kilogram (kg) of body weight.
Sample Dosage Calculation: For a person weighing 70 kg:
- 200 mcg x 70 kg = 14,000 mcg or 14 mg
- This dosage equates to 2.33 tablets of 6 mg ivermectin, typically rounded to two tablets for practicality, or 4.67 tablets of 3 mg ivermectin, typically rounded to five tablets.
General Recommendations for Ivermectin Use in Scabies:
- Initial Dose: 200 mcg/kg as a single oral dose.
- Follow-Up Dose: A second dose may be administered 7 to 14 days later to ensure complete eradication of mites.
- Crusted Scabies: In severe cases, such as crusted scabies, multiple doses in combination with topical treatments may be required.
- Administration: Take ivermectin with water, preferably on an empty stomach. Avoid alcohol, as it may increase the risk of side effects.
- Side Effects: Common side effects include nausea, diarrhea, headaches, and dizziness. Rare but severe side effects may include allergic reactions and neurological symptoms.
- Precautions: Seek medical advice, especially if pregnant, nursing, have pre-existing medical conditions, or are taking other medications.
- Combination Therapy: In cases of severe or resistant scabies, combination therapy with topical treatments such as permethrin may be recommended.
- Mass Treatment: To prevent reinfestation, treat all household members and close contacts simultaneously in outbreak situations.
Note: This information is for general reference. For personalized advice and specific dosage calculations, consult a healthcare provider.
Veterinary Ivermectin Products
Oral Paste for Animals:
- Ivermectin paste, often a 2% solution dissolved in water, is used for horses and cattle. It effectively eliminates most adult parasites, including lice, ticks, and mites, when applied to large areas of skin.
- This paste is not suitable for use in cats or dogs. Consult a veterinarian for appropriate treatment options for these animals, as ivermectin tablets are preferred.
- The paste should not be used on goats and lambs, as it may cause adverse reactions. Take care to avoid contact with the eyes, nose, or mouth of these animals.
- For best results, apply the paste before grazing begins and after milking has finished. It can also be applied the day before calving to help prevent lice infestation in newborn calves.
Ivermectin Use Across Species:
- Ivermectin 12 mg is a potent antiparasitic drug effective against lice and various types of intestinal worms in humans, pigs, cows, and horses. The formulation and dosage differ depending on the species being treated.
- It is crucial to consult a veterinarian for proper dosing, especially when treating different animals, as the ivermectin formulation used for one species may not be suitable for another.
Topical Use of Ivermectin
- Application: Apply a thin layer of cream or gel to the affected area twice daily. Wash your hands after application. Do not wrap or bandage the treated areas unless instructed.
- Precautions: Avoid contact with mucous membranes, including the mouth, nose, and eyes, unless using a formulation specifically designed for these areas. Protect your skin from direct sunlight, and wear protective clothing. Use sunscreen daily if exposed to the sun.
- Additional Safety: Avoid smoking or open flames when using topical ivermectin, as it may irritate the skin before it dries. Refrain from using heat sources such as hot tubs, saunas, and warm bedding until the skin is completely dry.